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Enantioselective HPLC of 15 . Top: all resolved stereoisomers. Colored traces show the analytical control of single isolated stereoisomer after semipreparative HPLC.

Journal: Journal of Medicinal Chemistry

Article Title: ( S , S )‑5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)‑ N ‑(1-oxo-1-((1-(pyridin-4-yl)ethyl)amino)propan-2-yl)‑1 H ‑indole-2-carboxamide, a New Dishevelled 1 and P‑Glycoprotein Dual Inhibitor as a Anticancer Agent

doi: 10.1021/acs.jmedchem.6c00706

Figure Lengend Snippet: Enantioselective HPLC of 15 . Top: all resolved stereoisomers. Colored traces show the analytical control of single isolated stereoisomer after semipreparative HPLC.

Article Snippet: Analytical HPLC analyses were carried out on a Jasco PU-980 HPLC pump equipped with a Rheodyne model 7125 (loop 20 μL) injector and coupled with a Jasco UV-975UV/VIS detector.

Techniques: Control, Isolation